Tetracaine Impurity 37 CAS 512175-79-0 (free base)
| CAS No. | 512175-79-0 (free base) |
| Molecular Formula | C13H19NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tetracaine Impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Tetracaine Impurity 37 (CAS 512175-79-0 (free base)), a pharmacopoeial impurity reference standard (molecular formula C13H19NO2HCl, MW 257.76 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Tetracaine Impurity 37 (C13H19NO2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H19NO2 HCl |
| Molecular Weight | 257.76 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Tetracaine Standards
- Tetracaine Impurity 7 (CAS 10012-47-2)
- Tetracaine Impurity 39 (CAS 101265-45-6)
- Tetracaine Impurity 14 (CAS 1029292-13-4)
- Tetracaine Impurity 17 (CAS 1056627-94-1)
- Tetracaine impurity 20 (CAS 1152620-27-3)
- Tetracaine EP Impurity B-d9 (CAS 1309935-92-9)
- Tetracaine Related Compound 1 (CAS 131719-63-6)
- Tetracaine Hydrochloride (CAS 136-47-0)
Recommended Standards
- Prilocaine Impurity 14 (CAS 120-66-1)
- Biotin Impurity 21 HBr (CAS 412308-26-0（free base）)
- Piperacillin Impurity 77 (CAS CATO-C4X-173277)
- 2-Phenoxy-N-(2-thienylmethyl)-1-ethanamine 805960-91-2 9980AE C13H15NOS (CAS 805960-91-2)
- 1-(Furan-2-ylmethyl)piperidine-3-carbohydrazide (CAS 415937-00-7)
- 6-Chloro-8-aminoquinoline (CAS 5470-75-7)
- 2-(1h-Imidazol-1-yl)-1,2,3,4-tetrahydronaphthalen-1-amine, mixture of diastereomers (CAS 1042771-99-2)
- 1-Benzylpiperidine-3-carbonitrile (CAS 91820-96-1)
- 3-(Trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acid (CAS 1214370-72-5)
- Neuropeptide VF (124-131) (human) (CAS 311309-27-0)
Why CATO?
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